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Fasting plasma glucose decreased by 4.7 mg/dL more in the semaglutide group than placebo, and HbA1c dropped by 0.24 percentage points more [4]

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Traditional probiotics, such as Lactobacillus and Bifidobacterium strains, can sometimes overpopulate the small intestine in those with SIBO, making soil-based options a better-tolerated choice for some individuals

Additionally, exposure to oridonin (ORI) at concentrations of 25 M (M) or higher for 48 h notably elevates cytosolic Ca 2+ concentration, promotes ceramide formation, and induces erythrocyte death through suicidal pathways ( To address these challenges, the development of advanced drug delivery systems is essential to improve ORIs solubility, enhance bioavailability, and reduce toxicity (Table 2